I started with the wedges and installed them this past week. Those, combined with a slightly lower Corbin seat, seem to have done the trick for me. Well, at least I'd say that I'm at about 90% of being all the way there. Did the 85 mile ride to work this morning, mostly interstate, with almost no numbness or wrist pain.
I think I am going to do a minor mod this weekend and add a .032 thick layer of rubber below the wedges and under the wedgy-washers to try and dampen out the last of the vibration. Maybe even a layer above the wedges, too. That's not enough thickness to affect the feel when turning, but may provide a sufficient impedence mismatch to dampen out any engine vibration that's coming up through the bars. (Heard that term somewhere and had to throw it in.)
I think the last thing that would do it for good would be to change the angle of the grips by having them more parallel to each other (by bending/rewelding them). I think there is a thread or two on this subject somewhere.