I have Motorcycle Larry's riser blocks, which essentially did nothing for or against the buzz. It greatly reduced the strain on my lower back muscles/spine, though (why I bought them), so it was a good move. YMMV buzz wise of course.
I did a bafflectomy, which reduced the buzz slightly. Plus the bike sounds meaner now...
I removed the muffler bolts that are next to the driver's pegs, and bent the tabs out/away from the frame. Mufflers are still on the bike where they were when I bent the tabs many many miles ago, and this helped reduce the buzz slightly. SISF/Steve recommends using isolator washers ('rubber' washers between the tabs and the frame), and has had good success with said isolation washers.
I shimmed the upper left motor mount with an extra washer (most guys end up doing this on the right side, my 'gap' was on the left though) to reduce torquing forces on the frame, this helped reduce the buzz slightly.
I packed my handlebars with material (small shot/bb's are suggested), which helped slightly.
I put the 'Wing sized' tire on the rear, which reduced RPMs by about 3%, hence increasing the 'buzz threshold' MPH wise slightly.
I put gel grips on my handlebars, which mitigated the buzz slightly.
I put in some NGK Iridium plugs. I think this helped slightly.
Everything I did by itself was almost insignificant on it's own, but together it has helped reduce the buzz enough to make it much more tolerable.
A lot of the buzz has went away since I broke in the bike (48,000 miles). She was much more buzzy when I first bought her. She had 1538 miles on the odo when I took her home (slightly used) from the dealer.
One thing that helps A LOT is a crampbuster. This allows you to relax your grip on the throttle a bit once you are at speed, hence less buzz is transmitted through the throttle into your right hand. This also (unconsciously) helps you relax your grip on the left handlebar too, so it's a win win.
I've went the foam grip route in the past (sorta), but currently I'm not feeling the need. The buzz is reduced enough now that I don't really notice it anymore. Also, I no longer employ the 'Vulcan Death Grip' on the handlebars, partially due to the crampbuster above.
Note that I have the 'protective' rider's gloves (Joe Rocket leather ones with the pads on top of the knuckles), and slip a pair of cotton gloves inside of them. The extra layer probably helps a bit with the buzz.
Proper valve adjustment helps with the buzz I think. I haven't checked my valves in a while now, though (well over 10K miles since the last adjust), so I need to crack that cover soon and see where I'm at. I've been meaning to get Steve's cams soon, hence my lack of worry r.e. the valve adjust, plus the bike is performing nicely.
Several have commented that after the first 3-4 valve adjusts, the valves seem to 'settle in', so adjustments aren't needed as often after that. This seems to be my case as well.
I hear that stick coils can help with the buzz, due to the 'cleaner/more consistent' spark. I want them...
I'm a fan of Shell Rotella T6. The bike has been running T6 (and T before that) since my first oil change, which I did at 3K on the odo. Dunno if this helped break in the motor any differently than regular oil, but I'm happy with my smooth shifts and the cams don't look that bad currently. Some minor pitting (most/almost all stock Connie cams have pitting issues), but nothing scary last time I did a valve adjust.
Steve's '7th gear' mod will help with the buzz significantly, as it will reduce your revs by 12% (hence you won't hit the 'buzz threshold' as soon MPH wise), and is just something every C10 Connie really should have. I still need to get one...
I hear that going to 'regular/different' handlebars helps a LOT with the buzz, so I was surprised to see one of the above posters not being happy with the helibars buzz wise. Helibars are different than regular tubular bars though, so that might have something to do with it.