ZG-- you have several of the farkles I'd love to add to my C14... (Heated Corbins being top of the list)..
Here are my impressions of the Throttlemeister, having had mine for over three years on my '08:
Easy to set once you get used to it: face it, a throttle lock isn't meant for in-town use. Setting it takes some deliberate motion, but using palm and little finger to set it while holding throttle with thumb and forefinger really isn't all that difficult. As others have suggested, the friction point can be preset where it won't take a lot of fiddling to get to a lock position.
Temperature makes a difference: Your heated grips may present an issue, so be prepared to reshim it until it works. I originally installed mine in winter and ended up having to shim it out some. The lock WILL make up for temp variations by virtue of it's long "throw"-- but dialing it in will make a huge difference on ease of use.
Having had "lever style" throttle locks (like the breakaway) on prior bikes, the ThrottleMeister was a hassle at first. But now I'm that used to it, I find this throttle lock to be an excellent solution for throttle hand fatigue on long distance rides. Setting the friction to where the unit just locks the throttle makes it easy to correct speed on minor grades as well.
It's a well built piece which looks like it's part of the bike. While it isn't as good as a full on electronic cruise control- it is a great alternative for those who (like me) only use it for a few minutes rest on a long ride.