In past years, with a sport touring group, we would ride the BRP from Waynesboro VA to Cherokee NC in two days. Gas up in Waynesboro and meet at Humpback Rocks Visitor Center around 10. We would stop for lunch at one of the visitor centers along the way and then gas up in Roanoke. We would stop for pie at Tuggles Gap (route
and continue on to get off the BRP near Hillsville for the night. Sadly we rarely stopped for sight seeing as the interest was on speed. So much so that you really didn't want to take your eyes off the road. The next morning would be into NC and on to Cherokee for the second night.
One of the things I've regretted by aligning myself with a 'faster' group was not enjoying the scenery and exhibits along the way although through the years I've eventually seen most of them. Of course, how you ride is up to you.
The speed limit on the BRP is 45mph for the most part. I've generally rode it a tad above 50 by myself. The Rangers won't bother you for that but if you do get a ticket it's Federal and pricey. I did have them blink their lights on me once, though. The busier parts of the BRP are in NC around Boone and Grandfather Mountain. More Rangers as well.
Some things with wheels to look out for are bicycles, autos, RVs, and other MCs. Bicycles will tend to bunch up and take up the road. You'll find RVs and autos all over but watch those blind corners and those idiots will stop and look at something in the middle of the roadway on a blind corner. Sport bikes I generally move over to the right and wave them on by to get them away from me. Cruisers in groups may go slow as molasses it seems but resist the urge to pass them all at once especially in corners. You'll get by them by and by.
The best time to ride the BRP is during the week. Stay away from it in the weekends if you can. You'll avoid most of the crowds that way.
Make sure that your bike is up to date on maintenance and your tires are good. I've seen that road chew up tires right before my eyes. Cell coverage is not the best on the BRP.
Check for construction on the BRP. You don't want to ride through a paving project in 90+ heat. Be aware of any detours. Check with the Park Service before you ride.
The best advice I can give is to take your time and enjoy it. There's much to see and do. And check out the websites associated with the BRP.
https://www.nps.gov/blri/index.htmhttps://www.blueridgeparkway.org/