Engines are interchangeable; electronics between early and later models not so much.
Certainly less probable between gen 1 and gen 2. And since he has a gen 1 (2009), the available pool of swappable stuff will be much smaller. As for within generations but of different years, I would say "probably." The worst part of all is that he will have to make SURE he gets at least one working fob with whatever CPU he can use, or the cost will skyrocket.
The engines are bullet proof. I wonder what happened?
Good question. If I had to guess (with zero information), I bet it is electrical...