Honda does sell a scooter with bike wheels. Can't remember the name, its a Kymco lookalike though. 150 cc's Automatic, 16 inch wheels, $4499USD. Check out the PCX, a bit smaller, 125cc's but also not a small scooter, $3999USD. I'd say from my experiences, THE biggest draw to these scooters is the automatic transmissions. A good thing to keep folks who otherwise would have either stopped riding or would have never tried it because they don't know or can't shift a manual tranny bike. Its also my personal opinion though to keep these auto transmissions on scooters ONLY, or at least offer manuals on future bikes for us who DO NOT want an auto.
http://powersports.honda.com/2010/sh150i.aspx